Engineering the Future of Kidney Recovery

Restoring kidney function.
Preventing dialysis.

Neukidney is developing therapeutic and regenerative platforms designed to improve outcomes for patients with chronic and acute kidney failure.

Kidney anatomy
Renal biotech platform

Neukidney is advancing therapies designed to restore kidney function.

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Product Spotlight

Renal Conduit System

A targeted regenerative renal delivery platform designed to support future therapy delivery directly into kidney tissue.

Patent-Pending Platform

Renal Conduit System

Targeted cellular therapy delivery platform

Our innovative design is a biocompatible conduit implanted subcutaneously and into the kidney parenchyma to allow for steady infusion of cellular therapy into the kidney tissue.

Kidney anatomy illustration
Investigational Platform Targeted renal therapy delivery
Targeted renal access

Designed to support delivery directly into renal parenchyma.

Regenerative focus

Built around future stem-cell-based and regenerative therapy approaches.

Preclinical support

Large-animal work supports intraparenchymal distribution of delivered cells.

Renal Conduit System
Renal Biotech Platform

A platform targeting high-morbidity, high-cost kidney disease.

Neukidney is positioned at the intersection of renal therapeutics, mitochondrial biology, NAD+ pathway optimization, and regenerative medicine.

Acute Recovery Program QRX-5 / Esenate

Renal recovery support for acute renal failure and ATN.

QRX-5 is being developed as a buffered NAD-focused therapy intended to accelerate renal recovery in hospitalized patients.

  • Target indication: acute renal failure / ATN
  • Current stage: Phase IIA signal; Phase 3 planning
  • Core objective: reduce morbidity and recovery burden
Regenerative Delivery Neukidney Catheter Platform

Catheter-enabled regenerative therapy delivery into renal tissue.

The regenerative catheter platform is designed to deliver stem-cell-based or regenerative therapies directly into renal parenchyma.

  • Target use: renal regeneration / advanced kidney disease
  • Current stage: Animal studies
  • Core objective: targeted renal parenchymal delivery
Our Mission

Prevent dialysis. Restore function. Reduce morbidity.

Neukidney's mission is to develop therapies that do more than slow kidney decline. The company is focused on therapies that may improve renal recovery, reduce dialysis dependency, decrease hospitalization burden, and improve quality of life for patients with kidney disease.

01
Restore function

Develop therapies designed around renal recovery, not only disease slowing.

02
Reduce dialysis burden

Target pathways that may delay or reduce progression to dialysis dependency.

03
Improve outcomes

Address chronic and acute kidney failure with a broader therapeutic platform.

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Pipeline Overview

Multiple programs. Multiple value inflection points.

Neukidney is advancing a development-stage renal biotechnology pipeline with potential milestones across clinical execution, CMC scale-up, regulatory alignment, and future strategic partnerships.

Program
Indication
Current Stage
Core Value Proposition
QRX-3 / Eseronate
Chronic Kidney Disease
Phase 3 planning
Multi-pathway NAD+ optimization designed to improve eGFR trajectory and reduce CKD progression.
QRX-5 / Esenate
Acute Renal Failure / ATN
Phase IIA signal
Designed to accelerate renal recovery in hospitalized acute renal failure patients.
Neukidney Regenerative Catheter
Renal regeneration / ESRD
Animal studies
Catheter-directed renal parenchymal delivery platform for regenerative therapy.
MD-1 / MD-5 Program
Hemodynamic instability / preclinical renal applications
Preclinical
Early-stage program targeting high-risk cardiovascular-renal instability.
Development Strategy

A multi-pathway approach to renal recovery.

Neukidney is focused on therapies that may improve renal recovery, reduce dialysis dependency, decrease hospitalization burden, and improve quality of life for patients with kidney disease.

Innovation in action

Targeting renal injury from multiple directions.

The company's development strategy combines NAD+ biology, mitochondrial support, renal recovery therapeutics, and catheter-enabled regenerative delivery.

01

NAD+ pathway optimization

Designed to improve mitochondrial energy transfer and support renal cellular recovery.

02

Inflammation and fibrosis reduction

Programs are intended to reduce inflammatory cytokines and fibrosis-related tissue damage.

03

Targeted regenerative delivery

The catheter platform is designed to support direct renal parenchymal delivery of regenerative therapy.

Engineering the future of kidney recovery

Executive Team

Harvard-trained and clinically experienced leadership.

Neukidney's leadership and advisory team is built to support the transition from clinical proof-of-concept to Phase 3 execution, manufacturing scale-up, and future regulatory submission.

Dr. Ebima Clifford Okundaye
Co-Founder

Dr. Ebima Clifford Okundaye

Co-Founder of Neukidney, leading the company's vision to develop therapies that restore kidney function and reduce dialysis dependency. Dr. Ebima is a nephrologist in Pearland, Texas, specializing in kidney care and hypertension management.

Dr. Sophie Oliff
Co-Founder

Dr. Sophie Oliff

Co-Founder of Neukidney, leading translational strategy and patient-centered development. A Fulbright scholar with experience leading healthcare implementation strategies for the Ministry of Health, New Zealand, and a Harvard Master's candidate.

Joseph Onyeizu
Director

Joseph Onyeizu

Harvard alumni with a PhD and MBA degree. An industry expert with over 10 years management experience at Merck Pharmaceuticals, currently leading the global strategy division for Keytruda studies.

Calethia Hodges
Advisor, Harvard University

Calethia Hodges

Advisor with deep expertise in renal therapeutics and clinical development strategy. President and co-founder of Trialteam.org, Harvard alumnus with 20+ years leading large clinical trials. Previously founded Hodges Clinical Group (acquired 2022).

Shepard Bentley
Advisor

Shepard Bentley

Consultant with extensive experience serving as a liaison for companies navigating FDA approval processes. Currently serves as the FDA Liaison for the company, providing critical regulatory guidance and strategic direction.

Investor & Clinical FAQ

Frequently asked questions

Clear answers about Neukidney's investigational therapies, development stage, regulatory status, and partnership opportunities.

Research-stage platform

Have questions about Neukidney?

This section keeps the language careful, credible, and useful for investors, clinicians, research partners, and strategic collaborators.

Start a conversation

QRX-3 is Neukidney's lead patented renal therapy for chronic kidney disease. It is designed as a multi-pathway NAD+ optimization therapy intended to support mitochondrial energy transfer, reduce inflammatory signaling, and protect kidney tissue.

QRX-5 is being developed as a buffered NAD-focused therapy for acute renal failure and acute tubular necrosis, with the goal of accelerating renal recovery in hospitalized patients.

The regenerative catheter platform is a patent-pending renal delivery approach designed to deliver regenerative therapy directly into renal parenchyma.

No. Neukidney's therapies and regenerative platform should be presented as investigational and subject to appropriate clinical, scientific, manufacturing, and regulatory review.

Neukidney is seeking strategic investors, board members, clinical development partners, and pharmaceutical collaborators to support Phase 3 execution, CMC scale-up, regulatory submission, and global commercialization.

You can contact Neukidney at info@neukidney.com or call 832-831-6135.

Partner With Neukidney

Support the next stage of kidney recovery innovation.

Neukidney is seeking strategic investors, board members, clinical development partners, and pharmaceutical collaborators to support Phase 3 execution, CMC scale-up, regulatory submission, and global commercialization.

Contact Neukidney Inc. 331 Burke Road, Suite 306, Houston, Texas Phone: 832-831-6135 Email: neukidneypharma.com